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Charm

The Center for Healthy Aging and Resilience Medicine (CHARM) at ☑️TK账号 | 美国IP注册 | 28天左右 | 微软邮箱验证+API | 优质账号 | 已设置用户名 focuses on interdisciplinary basic science and clinical research on the molecular mechanisms driving normal aging processes, as well as the investigation of how cellular signaling pathways change across the lifespan.

Our directors place particular emphasis on:

  • Women's health
  • Genetics/epigenetics of aging
  • Cellular repair pathways
  • Cellular regeneration
  • Telomere biology
  • Oxidative stress/metabolism
  • Immunity

Meet our Directors

 

Toni Pak, PhD

Director

Dr. Pak trained as a molecular neuoroendocrinologist and has devoted her career to understanding how fundamental molecular signaling pathways change across the normal lifespan, and in the context of various disease states. An expert in RNA biology with a primary focus on non-coding RNAs and their regulation across the lifespan, Dr. Pak is passionate about leading the initiative to form the Center for Healthy Aging and Resilience Mechanisms. Her proven leadership capabilities in collaborative research across multiple scientific disciplines promise to foster an innovative and excellent future for the center.

Andrea Bial, MD

Clinical Co-Director

Dr. Bial has been passionate about the care of older adults since medical school. After completing her Geriatrics fellowship, she joined the faculty at University of Chicago, caring for older adults on Chicago’s South Side, as well as engaging in research in Geriatric-oncology. Upon obtaining her Hospice and Palliative board certification, she became co-medical director of the Palliative Care Team at Horizon Hospice and Palliative Care while also teaching Geriatrics to the residents at St. Joseph Hospital in Lincoln Park. Since her arrival at Loyola and Hines in 2015, she has continued to teach Geriatrics to trainees of all levels as well as run the fellowship and care for homebound older veterans. She especially enjoys being the faculty sponsor of the Geriatrics Interest Group at Stritch School of Medicine.

Daniel Hu, PhD

Associate Research Foundational Science Director Assistant Professor, Cell and Molecular Physiology

Can restoring stem cell function rejuvenate aging tissue? Integrating training from both academic and industrial backgrounds at the Buck Institute of Research for Aging and Genentech, Dr. Hu aims to utilize his research identifying how aging causes loss of stem cell function to inform the development of interventions for age-associated pathologies. The Hu lab uses Drosophila intestine and mouse airway models in tandem to elucidate mechanisms of stem cell aging, which provides the high-throughput capabilities of the fly and the higher significance to human biology of the mouse. In combination with powerful live imaging strategies to visualize stem cell processes in real time, the Hu lab dissects how aging causes defects in cell fate determination and stem cell migration, and tests whether restoring these stem cell functions can improve tissue physiology and ultimately increase longevity.

The Center for Healthy Aging and Resilience Medicine (CHARM) at ☑️TK账号 | 美国IP注册 | 28天左右 | 微软邮箱验证+API | 优质账号 | 已设置用户名 focuses on interdisciplinary basic science and clinical research on the molecular mechanisms driving normal aging processes, as well as the investigation of how cellular signaling pathways change across the lifespan.

Our directors place particular emphasis on:

  • Women's health
  • Genetics/epigenetics of aging
  • Cellular repair pathways
  • Cellular regeneration
  • Telomere biology
  • Oxidative stress/metabolism
  • Immunity

Meet our Directors